"what the body does to the drug" seeks to provide a mathematical basis for the description of these processes
is a combined science
Pharmacokinetics can be considered a "phase" of drug action.
solubility is a key issue for pharmacokinetics
Pharmacokinetics defines 4 fundemental paramters
can't measure drug concentration directly that effect is correlated to the concentration
applied pharmacokinetics is to obtain experimental data
The 4 main topics of Pharmacokinetics are abbreviated ADME,
are covered in more detail in the main article on ADME
Limitations of PharmacokineticsEdit
limit of the assumption that plasma concentration is representative of the target locality concentration that the response depends only on the concentration at the target site
Anon (n.d.) ‘“Pharmacokinetics” in Medicinal Chemistry – principles and practice’, [online] Available from: http://learn2.open.ac.uk/pluginfile.php/388970/mod_resource/content/1/JEFFREY.pdf (Accessed 12 May 2012).